The DMD Hub Toolkit is a selection of expanding resources for industry and DMD-Hub sites aimed at upskilling sites and offering pragmatic support in trial set, thereby promoting a common approach to conducting clinical trials at sites in the UK.
The tools are grouped by category below. Each tool is either publicly available or confidential (accessible via a request form).
Read more below:
It is well-understood that receiving the best care can dramatically improve the quality of life and life expectancy of individuals with Duchenne muscular dystrophy, enabling them to lead fulfilling, independent lives into adulthood. The importance of international care recommendations cannot be underestimated.
These recommendations are currently being reviewed by the DMD Care UK project, to ensure that all patients with DMD have access to the best care.
At this time of national emergency, we are here to support both clinicians and patients in whatever ways we can.
In this section, you will find a series of webpages and downloads to provide you with the most up-to-date information on the virus, from guidelines on clinical trials and action plans, to advice for patients with DMD.
TREAT-NMD is a network for the neuromuscular field that provides an infrastructure to ensure that the most promising new therapies reach patients as quickly as possible. Since its launch in January 2007 the network's focus has been on the development of tools that industry, clinicians and scientists need to bring novel therapeutic approaches through preclinical development and into the clinic, and on establishing best-practice care for neuromuscular patients worldwide.
Guidance documents for becoming audit ready.
Tools to help with consenting in clinical trials.
The DMD Hub has created this costing guidelines template to help industry and trial sites determine fair and uniform costing throughout all clinical trial sites in the UK.
Use these tools to help with muscle biopsy collection and processing.
These tools cover the use of MRI in DMD clinical trials.
Use these tools for support completing ethics and Integrated Research Application System (IRAS) forms.
Publications relating to DMD clinical trials.
In collaboration with Duchenne UK, the DMD Hub has been working on a series of webinars to address some of the key issues around clinical trials in the UK, including what happens when a trial ends, and everything patients need to know about gene therapy.
Bringing in patients, clinicians and industry representatives, these webinars help facilitate discussions around these important issues, and to identify areas where the DMD Hub can support.