The DMD Hub’s Clinical Trial Finder brings together trustworthy and reliable information on all existing and upcoming trials for Duchenne Muscular Dystrophy in the UK.
Our Clinical Trial Finder has been designed for patients and caregivers, to be as accessible and comprehensive as possible. Every trial has information on outcome measures, inclusion criteria and an easy to understand lay summary. You can use search filters to find trials that are relevant to you and download a fact sheet for each trial. The information on each trial has been sourced directly from industry and hospitals and is verified by Duchenne UK and the DMD Hub management team.
Join The DMD Hub, to stay up-to-date with the latest DMD clinical trials updates.
IMPORTANT NOTICE REGARDING THE IMPACT OF COVID-19 ON CLINICAL TRIALS IN THE UK
Due to the impact of COVID-19 all clinical trial sites in the UK have implemented some restrictions on screening, randomisation and study visits.
The situation is changing on a daily basis and it is difficult for the sites to provide us with updates proactively. Therefore, in order to ease the burden on sites, we will only update the clinical trail finder if a study is fully recruited or terminated. Patients should be aware that studies currently 'recruiting' on the clinical trail finder may be subject to some restrictions.
Patients should contact sites directly for additional information on studies they believe they would be eligible to participate in.
Patients currently enrolled into a clinical trail will be contacted directly by their site to discuss how the clinical trial is affected at that site.
= Fully recruited
= Not yet recruiting
= Enrolling by invitation
This study is designed to study a number of genes considered to be modifiers for DMD. This translational research will identify and obtain DNA samples and clinical information from 400 cases with DMD. This data will then be grouped into clinically and genetically defined groups. The DNA of the participants will be analysed and correlated to motor performance, age at loss of ambulation, severity of respiratory failure and severity of cardiac impairment.
The SIDEROS trial is designed to determine the effect of idebenone at delaying the loss of lung function in patients with DMD, receiving glucocorticoid steroids. This is a placebo-controlled trial.
This study is a stage 3 trial of Sanethera's Idebenone drug and it's long term effects in delaying the loss of lung function in patients with DMD, receiving glucocorticoid steroids. This trial is only open to those patients who were part of the SIDEROS trial and are currently taking steroids.
This study will compare the change in stair climb test and other functional tests in patients taking givinostat and patients taking a placebo. Givinostat has potential anti-inflammatory, antifibrotic and proregenerative effects.
Please note this protocol was amended early 2019.
Stay informed about the latest DMD clinical trials and keep up-to-date with the latest news from the DMD Hub.