Alder Hey is a leading paediatric research centre. Our aim is to be a world class centre for research, innovation and education, and we aim to pioneer and develop new treatments for children and young people.
This is made possible by a comprehensive range of paediatric specialist and general clinical services, its expert healthcare professional workforce, a large multidisciplinary and experienced clinical research delivery workforce and its extensive access to a supra-regional population of children and young people. At any time there are over 200 clinical research studies taking place, ranging from observational studies to complex, interventional clinical trials supported by the Clinical Research Division including the NIHR Alder Hey Clinical Research Facility. Alder Hey is the UK’s largest centre for volume of recruitment into children’s research studies.
Institute in the Park
Alder Hey Children’s NHS Foundation Trust
Eaton Road, Liverpool L12 2AP
|Wave Life Sciences Exon 51||Not yet recruiting|
|Vamorolone Phase 2b (VISION-DMD)||Not yet recruiting|
|Tamoxifen (TAMDMD)||Not yet recruiting|
|Summit- Ezutromid (PhaseOut DMD)||Recruiting|
|Italfarmaco- Givinostat (EPIDYS)||Ongoing (fully recruited)|
|FOR-DMD||Ongoing (fully recruited)|
|Domagrozumab phase 2||Ongoing (fully recruited)|
Dr Spinty studied medicine at the University of Hamburg, Germany. Initial clinical training was in Germany but subsequently in the UK.
He completed his specialist Paediatric and Paediatric Neurology training in Leeds, UK and was appointed as Consultant Paediatric Neurologist and lead clinician for the neuromuscular services at Alder Hey Children’s Hospital in 2004. The service was again granted “centre of clinical excellence” status in December 2015.
Since 2010 Dr Spinty has been the lead for neuromuscular research at Alder Hey. He is the Principal Investigator for currently 9 studies related to Duchenne Muscular Dystrophy.
He has founded and is the chair of the North West Adult and Paediatric Neuromuscular Network that achieved excellence status in December 2016.
Dr Lemon graduated from the University of Southampton in 2008 and started her paediatric training in 2011, after doing a Masters at the Liverpool School of Tropical Medicine. She has had a longstanding interest in neurological conditions, neurodisability and global child health and developed an interest in research whilst doing her Masters degree. From 2012-2015, she combined academic with clinical training by undertaking an Academic Clinical Fellow post in the Institute of infection and Global Health at the University of Liverpool, working on research related to paediatric encephalitis.
In 2015-2016, she spent a year working in Malawi (a small country in Africa), working both in the hospital and completed a research project involving translation, cross cultural adaptation and field testing of two questionnaire tools to assess the impact of child disability.
Dr Lemon is currently one of the neuromuscular clinical research fellows at Alder Hey. She applied for the post to further her experience of clinical trials and paediatric neuromuscular conditions.
Dr Turner studied medicine at the University of Liverpool and graduated in 2015 with an honours degree. She developed an interest in paediatrics early on as a student, choosing to complete paediatric rotations in both St Helens and Knowsley NHS Foundation Trust and Blackpool Victoria NHS Foundation Trust. Dr Turner completed her medical elective in Ghana Akim Oda Government Hospital which included working on the medical, surgical and paediatric wards.
After graduation she completed her Foundation Training at Warrington and Halton NHS Foundation Trust. Her paediatric foundation placement was undertaken at Alder Hey Children’s Hospital on the general paediatric and diabetes team. Dr Turner was involved in a project determining the accuracy and user experience of the new novel flash glucose monitoring system. She presented the findings at the national British Society of Paediatric Endocrinology and Diabetes conference. This not only confirmed her interest in paediatrics but also sparked an interest in research.
In 2017 Dr Turner successfully applied for the post as Neuromuscular Clinical Research Associate here at Alder Hey. Dr Turner is looking forward to starting her speciality paediatric training at the end 2018.
Aiste started her journey to biomedical research in Lithuania, where she got an equivalent of the 1st class honours degree in Biochemistry from Vilnius University. She then took a PhD offer from the University of Manchester and moved to the UK to investigate electrophysiological properties of excitable cells with the main focus on vascular smooth muscle. She was awarded a PhD in Physiology in 2012 and then took a post-doctoral project at The University of Oxford to study pharmacology and biophysics of specialised proteins called ion channels that are embedded in cell membranes and regulate their function. Upon successful completion of the project Aiste was awarded an Early Investigator’s Prize for her publication on ion channel characteristics in the Journal of Physiology.
Aiste then moved back to the University of Manchester, where she joined a cardiac research group. She was investigating structural and functional properties of ovine atrial transverse tubules, i.e. extensions of the cell membrane penetrating towards the interior of the cell. In parallel to this project she also got an Associated Fellowship Recognition by the Higher Education Academy for her contributions to teaching.
After successfully completing two biomedical research projects Aiste moved to clinical research and took a clinical trials coordinator’s role at Alder Hey Children’s Hospital. She manages different aspects of the Duchenne muscular dystrophy trials portfolio from trial initiation to completion. Aiste is extremely pleased to see new pharmacological targets being identified for the treatment of this muscle wasting disease. She hopes that new therapies would lead to a life-changing breakthrough in clinical practice.
Originally from Cork, Ireland Sarah moved to Bristol in September 2000 to study physiotherapy at the University of West of England in Bristol. After qualifying in 2003 Sarah took up her first post as a junior physiotherapist in Hope Hospital in Salford until moving to Alder Hey Children’s Hospital, Liverpool in 2006 as a Senior Physiotherapist. She worked across all acute and community paediatric specialities gaining an interest in Neurology. In 2010 Sarah started a MRes degree at the University of Liverpool which allowed her to complete research projects of interest to her and her area of clinical work. After a break for maternity leave Sarah moved into the neuromuscular physiotherapy team in 2012, initially as a temporary position and then became a permanent member of the team in 2014. In 2015 she completed her MRes in clinical Science with distinction. Having gained a keen interest in research during her MRes studies Sarah took the opportunity to take up the research physiotherapist post as part of the Alder Hey neuromuscular team in collaboration with Duchenne UK.
Tim has been appointed as a Duchenne Muscular Dystrophy research nurse at Alder Hey. He qualified as a staff nurse at Alder Hey in 2003 and worked on the regional oncology unit at Alder Hey.
He became a research nurse at the Clinical Research Facility in 2012, where he has lead on multiple early phase research studies, including oncology studies, studies in theatre, and gastroenterology studies amongst others. Also, he has led on 2 studies that recruited the first global patients to the study.
Away from work he is a family man and spends most of his weekends watching his children play multiple sports! He is a keen cyclist and plays football socially once a week.